The Joes are framed for stealing nuclear warheads from Pakistan by Zartan (Arnold Vosloo) who is impersonating the President of United States (Jonathan Pryce). The entire team is eliminated in a military strike, with Duke (Channing Tatum) as one of the casualties. Roadblock (Dwayne Johnson), Flint (D.J. Cotrona) and Lady Jaye (Adrianne Palicki ) are the only survivors.
Meanwhile, Storm Shadow (Byung-hun Lee) and ex-Joe Firefly (Ray Stevenson) rescue Cobra Comandor (Luke Bracey) from an underground maximum-security prison in Germany. Storm Shadow is injured during the escape, and retreats to a temple in the Himalayas to recover. Upon learning that he is alive, the Blind Master (RZA), leader of the Arashikage Clan, sends Snake Eyes (Ray Park) and his apprentice Jinx (Elodie Yung), Storm Shadow's cousin, to capture Storm Shadow so he can answer for the murder of his uncle, the Hard Master.
Roadblock, Flint, and Lady Jaye return to the United States where they set up a base of operations in a rundown gym. After Zartan announces that Cobra will replace the Joes as America's main protective unit, Lady Jaye deduces that someone is impersonating the President, and Roadblock leads them to Genaral Joseph Colton (Bruce Willis), who provides them with weapons and helps them infiltrate a fundraising event that the President will be attending. Lady Jaye steals a sample of the President's DNA and confirms that he is Zartan. They escape after a brief confrontation with Firefly and Zandar (Matt Gerald), the head of the Presidential Detail and a member of Cobra.
Snake Eyes and Jinx locate and capture Storm Shadow after a battle with ninjas and take him back to Japan, where Storm Shadow reveals that Zartan murdered the Hard Master and he joined Cobra to avenge his uncle. Storm Shadow then accompanies Snake Eyes and Jinx as they join the Joes' efforts to stop Cobra.
Zartan invites the world leaders to a summit, where he blackmails them into disabling their nuclear arsenals, and reveals that he has created Project Zeus: seven orbital kinetic bombardment weapons of mass destruction at his command. He destroys central London to prove his superiority, and threatens to destroy other capitals if the countries don't submit to Cobra. However, Storm Shadow betrays Cobra Commander and kills Zartan, revealing Cobra's deception to the world leaders. While Snake Eyes, Jinx, and Flint fight Cobra's soldiers, Cobra Commander activates the remaining six weapons and instructs Firefly to protect the launch device. Firefly is killed in combat by Roadblock, who deactivates and destroys the orbital weapons. Meanwhile, Colton and Lady Jaye rescue the President.
Cobra Commander escapes during the battle and Storm Shadow disappears after avenging his uncle. The real President addresses the nation at a ceremony where Roadblock, Jaye, Flint, Jinx, and Snake Eyes are commemorated as heroes. Colton thanks each of them, and presents Roadblock with the gun of General Patton, for when he finally finds Cobra Commander. Roadblock proudly raises the colt m1911 in the air and lets out one shot.
CASTING
- Dwayne Johnson as Roadblock
- Jonathan Pryce as the President of the United States
- Byung-hun Lee as Storm Shadow
- Ray Park as Snake Eyes
- Elodie Yung as Jinx
- Ray Stevenson as Firefly
- D.J. Cotrona as Flint
- Adrianne Palicki as Lady Jaye
- Channing Tatum as Duke
- Luke Bracey as Cobra Commander
- Bruce Willis as General Joseph Colton